D.L. Hughley: Feb. 3, Apr. 16-17, June 20, 2012

Howie Mandel: Feb. 1, Apr. 9-10, June 14, 2012

Jesse Palmer: Jan. 12, Apr. 23-24, June 13, 2012

Jerry O'Connell: Nov. 25, 2011, Feb. 9-10, Mar. 23, 26-27, June 11-12, July 19, 2012

Jerry O’Connell born and raised in New York City, began his acting career at age 11 when he co-starred as Vern Tessio in the classic Rob Reiner film Stand By Me. After graduating with a BFA from New York University, he returned to feature film work, notably receiving critical acclaim for his role as quarterback Frank Cushman in Jerry Maguire with Tom Cruise. Additional screen credits: Scream 2; Can’t Hardly Wait; Mission to Mars; Tomcats; the Jerry Bruckheimer-produced comedy Kangaroo Jack; Yours, Mine and Ours; Man About Town (with Ben Affleck); Obsessed (with Beyoncé Knowles); and Dimension Films’ recent remake of the cult classic Piranha 3D.

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Andy Samberg: June 8, 2012

"Saturday Night Live" cast member Andy Samberg makes his co-host debut with Kelly today.

Neil Patrick Harris: Nov. 28, Dec. 2, 2011, Feb. 27, Apr. 6, June 6-7, 2012

Harris currently stars as Barney Stinson on the hit CBS sitcom, “How I Met Your Mother,” a role which has garnered him multiple Emmy and Golden Globe Award nominations, as well as a People’s Choice Award for Favorite TV Comedy Actor, and a Critics’ Choice Award for Supporting Actor in a Comedy Series. Earlier this year he starred in the live-action/animated feature “The Smurfs,” and he can currently be seen onscreen in “A Very Harold and Kumar 3D Christmas.”

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